We are living at a unique time in biomedical history. We've seen a revolution in complementary forces that are helping us change the way we think of medicine. For the first time, we have a complete "parts list" of genes and other building blocks, which means we can personalize therapies. At the same time, we have an IT revolution that lets us gather data, mine it and visualize it in sophisticated ways, and act on it in real time in the ICU or predict problems with anticipatory medicine. And new technology allows us to probe the human organism through imaging and other areas, to visualize what's going on. Add to those the twenty-first century patients, who are well-informed, empowered, and incredible advocates for change. These forces are converging to allow us to take on the big problems, and have a good chance of finding solutions to ones that have frustrated us for so long. Uniquely positioned to make a difference. Embedded within Emory University, we have links to the business school, the department of chemistry, and many other academic resources that are traditionally outside the realm of health care. We have hospitals where we teach the next generation of health professionals to provide the most advanced, compassionate patient care. We have research institutes and government and industry partnerships racing to find the next discovery or cure. We have all of this in one location, with a structure that allows those important interdisciplinary interactions to occur. With these resources and our team of bold thinkers who are willing to take risks in order to achieve something great, we believe there are no limits to what we can accomplish.